Interleukin-17: A Social Cytokine

Abstract

Some children with autism spectrum disorder (ASD) show behavioral improvements when experiencing inflammation accompanied by fever; however, little is known about the mechanisms that underlie these beneficial effects. In a recent issue of Nature, Reed and colleagues demonstrate that the production of interleukin-17 (IL-17) during inflammation promotes social behavior in mouse models of neurodevelopmental disorders.

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Citation

Hoogenraad, C C & Riol-Blanco, L 2020, 'Interleukin-17: A Social Cytokine', Cell, vol. 181, no. 3, pp. 517-519. https://doi.org/10.1016/j.cell.2020.03.060