The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy
Publication date
2024
Authors
Falke, Charlotte M
Karapinar, F.
Bouvy, Marcel
Emmelot, Mariëlle
Belitser, S.
Boland, Benoit
O’Mahony, Denis
Murphy, Kevin D.
Haller, Moa
Salari, Paola
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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cc_by
Abstract
Aim: To explore the association between medication use-related factors and quality of life in older hospitalised patients with polypharmacy. Findings: Hyperpolypharmacy, a high anticholinergic and sedative burden, presence of multiple prescribing omissions (based on START criteria), the use of opioids, antibiotics and benzodiazepines, and high medication complexity were associated with a lower quality of life. Message: Due to the association with quality of life, evaluating medication use-related factors, especially medication complexity as a novel factor, is important for hospitalised older patients with (hyper)polypharmacy.
Keywords
HRQoL, Medication complexity, Medication use, Polypharmacy, Quality of life, Gerontology, Geriatrics and Gerontology
Citation
Falke, C, Karapinar, F, Bouvy, M, Emmelot, M, Belitser, S, Boland, B, O’Mahony, D, Murphy, K D, Haller, M, Salari, P, Schwenkglenks, M, Rodondi, N, Egberts, T & Knol, W 2024, 'The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy', European Geriatric Medicine, vol. 15, no. 6, pp. 1713–1723. https://doi.org/10.1007/s41999-024-01036-4