Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review

Publication date

2018-01-01

Authors

Postema, Floor A M
Hopman, Saskia M J
Hennekam, Raoul C M
Merks, Johannes H MISNI 0000000396307818

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

taverne

Abstract

Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.

Keywords

cancer, consequences, genetic predisposition to disease, pediatrics, Taverne, Pediatrics, Perinatology, and Child Health, Hematology, Oncology

Citation

Postema, F A M, Hopman, S M J, Hennekam, R C M & Merks, J H M 2018, 'Consequences of diagnosing a tumor predisposition syndrome in children with cancer : A literature review', Pediatric Blood & Cancer, vol. 65, no. 1, e26718. https://doi.org/10.1002/pbc.26718