Biomimetic synthesis of neodihydrothebaine and bractazonine from thebaine

Publication date

1984

Authors

Salemink, C.A.
Theuns, H.G.
La Vos, G.F.
Noever de Brauw, M.C. ten

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Abstract

Photochemical irradiation of the morphinan alkaloid thebaine 1 followed by reduction, affords the dibenz[d,f]azonine alkaloids neodihydrothebaine 2 and bractazonine 3, in a sequence paralleling the proposed biosynthesis of these alkaloids in Papaver bracteatum.

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