Author Correction: The kinase TNIK is an essential activator of Wnt target genes (The EMBO Journal, (2009), 28, 21, (3329-3340), 10.1038/emboj.2009.285)

Publication date

2025-08

Authors

Mahmoudi, Tokameh
Li, Vivian S W
Ng, Ser Sue
Taouatas, Nadia
Vries, Robert G J
Mohammed, Shabaz
Heck, Albert J.
Clevers, HansISNI 0000000043961208

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Supervisors

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Comment

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Abstract

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The authors provided the original source data, which confirms that no duplication occurred in the original dataset. For transparency, the original source data is published with this author correction. Author Statement: In the original publication, an error was identified in Figure 1 (IP TCF4, WB β-catenin in the villus compartment). A duplication occurred, resulting in a small, duplicated segment at the end of the panel. The original source data has been located and is provided with this author correction. The experiment was performed in February 2009, as indicated on the films. Two different exposures of the same panel are included—one unannotated and one with annotations for clarification. The original data confirms that a duplication was present only in the published figure; however, no data was obscured by this duplication. The data clearly shows the absence of interaction between TCF4 and beta-catenin in the villus compartment (confirming our mass spectrometry data and expected given the absence of Wnt signalling in the villus compartment). This correction does not alter the conclusions of the study.

Keywords

General Neuroscience, Molecular Biology, General Biochemistry,Genetics and Molecular Biology, General Immunology and Microbiology

Citation

Mahmoudi, T, Li, V S W, Ng, S S, Taouatas, N, Vries, R G J, Mohammed, S, Heck, A J & Clevers, H 2025, 'Author Correction : The kinase TNIK is an essential activator of Wnt target genes (The EMBO Journal, (2009), 28, 21, (3329-3340), 10.1038/emboj.2009.285)', EMBO Journal, vol. 44, no. 15. https://doi.org/10.1038/s44318-025-00393-5