Log In

Glioma EVs Contribute to Immune Privilege in the Brain

Files

1-s2.0-S2405803319300974-main.pdf (591.54 KB)

Publication date

2019-07-01

Authors

Abels, Erik R.
Broekman, MariekeISNI 0000000394030739
Breakefield, Xandra O.
Maas, Sybren L N

Editors

Advisors

Supervisors

DOI

https://doi.org/10.1016/j.trecan.2019.05.006

Document Type

Article

Metadata

Show full item record

Collections

UMC Repository
Open Access logo

License

taverne

Abstract

Glioblastoma cells release extracellular vesicles (EVs), sometimes referred to as microvesicles and exosomes, to transfer immune modulating molecules to immune cells, resulting in an immune privileged microenvironment. Here we discuss the potential EV-mediated mechanisms underlying glioma immune modulation, as well as the technical difficulties in studying these interactions.

Keywords

exosomes, extracellular vesicles, glioblastoma, glioma, immunity, Taverne, Oncology, Cancer Research

Citation

Abels, E R, Broekman, M L D, Breakefield, X O & Maas, S L N 2019, 'Glioma EVs Contribute to Immune Privilege in the Brain', Trends in Cancer, vol. 5, no. 7, pp. 393-396. https://doi.org/10.1016/j.trecan.2019.05.006

URI

https://dspace.library.uu.nl/handle/1874/438925