Clinical and dosimetric considerations for Y90: recommendations from an international multidisciplinary working group
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Publication date
2019-07-01
Authors
Salem, Riad
Padia, Siddharth A.
Lam, Marnix
Bell, Jon
Chiesa, Carlo
Fowers, Kirk
Hamilton, Bonnie
Herman, Joseph
Kappadath, S. Cheenu
Leung, Thomas
Editors
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Document Type
Article
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taverne
Abstract
The TheraSphere Global Dosimetry Steering Committee was formed in 2017 by BTG International to review existing data and address gaps in knowledge related to dosimetry. This committee is comprised of health care providers with diverse areas of expertise and perspectives on radiation dosimetry. The goal of these recommendations is to optimize glass microspheres radiation therapy for hepatocellular carcinoma while accounting for variables including disease presentation, tumour vascularity, liver function, and curative/palliative intent. The recommendations aim to unify glass microsphere users behind standardized dosimetry methodology that is simple, reproducible and supported by clinical data, with the overarching goal of improving clinical outcomes and advancing the knowledge of dosimetry.
Keywords
Hepatocellular carcinoma, Liver cancer, Radioembolization, Yttrium-90, Taverne, Radiology Nuclear Medicine and imaging
Citation
Salem, R, Padia, S A, Lam, M, Bell, J, Chiesa, C, Fowers, K, Hamilton, B, Herman, J, Kappadath, S C, Leung, T, Portelance, L, Sze, D & Garin, E 2019, 'Clinical and dosimetric considerations for Y90 : recommendations from an international multidisciplinary working group', European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 8, pp. 1695-1704. https://doi.org/10.1007/s00259-019-04340-5