Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory

Publication date

2024-06

Authors

Schouten, Robert
Schweitzer, Valentijn
van Marm, Sebastian
Rentenaar, R. J.ISNI 0000000392498872

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

cc_by

Abstract

MALDI-TOF MS identifications of microorganisms in a clinical laboratory were investigated, comparing steel targets with MBT Biotargets. By using MBT Biotargets, the score values of yeast identifications increased, whereas the score values of Gram-negative bacteria decreased. Switching to MBT Biotargets did not negatively impact overall frequencies of high confidence identifications.

Keywords

Biotarget, Identification, MALDI-TOF MS, Steel target, Yeast, Microbiology (medical), Infectious Diseases

Citation

Schouten, R K P, Schweitzer, V A, van Marm, S & Rentenaar, R J 2024, 'Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory', Diagnostic Microbiology and Infectious Disease, vol. 109, no. 2, 116270. https://doi.org/10.1016/j.diagmicrobio.2024.116270