Preservation of human heart valves for replacement in children with heart valve disease: past, present and future
Publication date
2024-03
Authors
Peters, Marijn C
Kruithof, B. P.T.
Bouten, C. V.C.
Voets, I. K.
van den Bogaerdt, A.
Goumans, M. J.
van Wijk, A
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
cc_by
Abstract
Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.
Keywords
Allograft heart valve, Congenital heart disease, Preservation, Tissue biobanking, Valve replacement, Biomaterials, Biomedical Engineering, Cell Biology, Transplantation
Citation
Peters, M C, Kruithof, B P T, Bouten, C V C, Voets, I K, van den Bogaerdt, A, Goumans, M J & van Wijk, A 2024, 'Preservation of human heart valves for replacement in children with heart valve disease : past, present and future', Cell and Tissue Banking, vol. 25, no. 1, pp. 67-85. https://doi.org/10.1007/s10561-023-10076-2