Carcinoid heart disease: A guide for screening and timing of surgical intervention
Publication date
2017
Authors
Hart, E A
Meijs, T. A.
Meijer, Ronald C.
Dreijerink, Koen M A
Tesselaar, M.E.
Groot, C. A. Uyl-de
Valk, Gerlof D.
Chamuleau, Steven
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Advisors
Supervisors
Document Type
Article
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Abstract
The cardiac manifestations of a neuroendocrine tumour are referred to as carcinoid heart disease (CaHD) and are associated with a poor prognosis. Surgical intervention is the only proven therapeutic option and may prolong survival and quality of life. No consensus has been reached internationally with regard to screening for CaHD and the optimal timing for surgery. Although limited evidence is available on this matter, a trend towards early surgery and subsequent reduced mortality has been observed. In this review we provide an overview of the current understanding and propose a protocol to guide cardiologists in the screening for CaHD and the timing of referral to a specialised surgical centre.
Keywords
Carcinoid heart disease, Hedinger syndrome, Screening, Surgery, Valvular disease, Cardiology and Cardiovascular Medicine, Journal Article, Review
Citation
Hart, E A, Meijs, T A, Meijer, R C A, Dreijerink, K M, Tesselaar, M E, Groot, C A U, Valk, G D & Chamuleau, S A J 2017, 'Carcinoid heart disease : A guide for screening and timing of surgical intervention', Netherlands Heart Journal, vol. 25, no. 9, pp. 471-478. https://doi.org/10.1007/s12471-017-1011-2