Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy
Publication date
2021-05-27
Authors
Rab, Minke A.E.
Bos, Jennifer
van Oirschot, Brigitte A
Straaten, Stephanie van
Kosinski, Penelope A
Chubukov, Victor
Kim, Hyeryun
Mangus, Heidi
Schutgens, Roger E G
Pasterkamp, Gerard
Editors
Advisors
Supervisors
Document Type
Letter
Metadata
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License
taverne
Abstract
Keywords
Taverne, Biochemistry, Immunology, Hematology, Cell Biology
Citation
Rab, M A E, Bos, J, van Oirschot, B, Straaten, S V, Kosinski, P A, Chubukov, V, Kim, H, Mangus, H, Schutgens, R E G, Pasterkamp, G, Dang, L, Kung, C, van Beers, E J & van Wijk, R 2021, 'Decreased activity and stability of pyruvate kinase in sickle cell disease : a novel target for mitapivat therapy', Blood, vol. 137, no. 21, pp. 2997-3001. https://doi.org/10.1182/blood.2020008635