First contact(in): The complete structure of contactin 2
Publication date
2024-10-03
Authors
Chataigner, Lucas M.P.
Janssen, B.J.C.
Editors
Advisors
Supervisors
Document Type
Article
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License
cc_by_nc_nd
Abstract
In this issue of Structure, Fan et al.1 report the structure of the full contactin 2 ectodomain, representing the first for the contactin family. The work reveals six immunoglobulin domains are essential for intercellular interactions, explores differences in proposed contactin 2 homodimerization mechanisms, and provides an updated model for contactin 2 organization on and between cells.
Keywords
Taverne, Structural Biology, Molecular Biology
Citation
Chataigner, L M P & Janssen, B J C 2024, 'First contact(in) : The complete structure of contactin 2', Structure (London, England : 1993), vol. 32, no. 10, pp. 1545-1547. https://doi.org/10.1016/j.str.2024.09.003