TCR engineered T cell therapy from concepts to clinic

Publication date

2019-04-09

Authors

Kierkels, Guido J J

Editors

Advisors

Supervisors

Kuball, JurgenORCID 0000-0002-3914-7806
Sebestyén, ZsoltORCID 0000-0001-6184-7676ISNI 0000000419408938

DOI

Document Type

Dissertation

Collections

Open Access logo

License

Abstract

The increased understanding of the human immune system and its ability to detect and eradicate tumor cells has led to a promising wave of novel therapeutics which have the potency to become the new standard of care. This thesis aims to contribute to the development of novel cell therapy products and the GMP manufacturing thereof.

Keywords

Tumor Immunology, Cancer Immunotherapy, T cell engineering, GMP manufacturing

Citation

Kierkels, G J J 2019, 'TCR engineered T cell therapy from concepts to clinic', UMC Utrecht.