Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover

Publication date

2020-01-09

Authors

Verster, J.C.ORCID 0000-0002-6455-2096ISNI 0000000076939752
Kruisselbrink, L Darren
Slot, Karin AISNI 0000000390131209
Anogeianaki, Aikaterini
Adams, Sally
Alford, Chris
Arnoldy, LizanneISNI 0000000493301637
Ayre, Elisabeth
Balikji, Stephanie
Benson, Sarah

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Abstract

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their "normal" drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their "regular" drinking level, considerably higher alcohol intake-irrespective of the absolute amount-may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

Keywords

alcohol, hangover, sensitivity, subjective intoxication, blood alcohol concentration

Citation

Verster, J C, Kruisselbrink, L D, Slot, K A, Anogeianaki, A, Adams, S, Alford, C, Arnoldy, L, Ayre, E, Balikji, S, Benson, S, Bruce, G, Devenney, L E, Frone, M R, Gunn, C, Heffernan, T, Hensel, K O, Hogewoning, A, Johnson, S J, van Lawick van Pabst, A E, van de Loo, A J A E, Mackus, M, Merlo, A, Murphy, R J L, Owen, L, Palmer, E O C, van Rossum, C J I, Scholey, A, Terpstra, C, Vatsalya, V, Vermeulen, S A, van Wijk, M & Stock, A-K 2020, 'Sensitivity to Experiencing Alcohol Hangovers : Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover', Journal of Clinical Medicine, vol. 9, no. 1, 179. https://doi.org/10.3390/jcm9010179