Sofosbuvir add-on to ribavirin treatment for chronic hepatitis e virus infection in solid organ transplant recipients does not result in sustained virological response
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Publication date
2019-08-01
Authors
Van Wezel, E. M.
de Bruijne, J
Damman, K.
Bijmolen, M.
Van Den Berg, A. P.
Verschuuren, E. A.M.
Ruigrok, G. A.
Riezebos-Brilman, A.
Knoester, M.
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Article
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Abstract
Ribavirin is effective for treating immunocompromised patients with chronic hepatitis E virus infection. However, ribavirin treatment is not always successful. We describe 3 solid organ transplant recipients treated with sofosbuvir and ribavirin after failing ribavirin monotherapy. Complete elimination of hepatitis E virus could not be achieved.
Keywords
chronic hepatitis E, sofosbuvir, solid organ transplant recipients, Journal Article
Citation
Van Wezel, E M, De Bruijne, J, Damman, K, Bijmolen, M, Van Den Berg, A P, Verschuuren, E A M, Ruigrok, G A, Riezebos-Brilman, A & Knoester, M 2019, 'Sofosbuvir add-on to ribavirin treatment for chronic hepatitis e virus infection in solid organ transplant recipients does not result in sustained virological response', Open forum infectious diseases, vol. 6, no. 8, ofz346. https://doi.org/10.1093/ofid/ofz346