Adaptive radiotherapy for breast cancer
Publication date
2023-03
Authors
De-Colle, C
Kirby, A
Russell, N
Shaitelman, S F
Currey, A
Donovan, E
Hahn, E
Han, K
Anandadas, C N
Mahmood, F
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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License
cc_by_nc_nd
Abstract
Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in target and organs at risk (OARs) anatomy occurring during the treatment course and integrates these in re-optimized treatment plans. Exploiting ART routinely in clinic may result in smaller target volumes and better OAR sparing, which may lead to reduction of acute as well as late toxicities. In this review MR-guided and CT-guided ART for breast cancer patients according to different clinical scenarios (neoadjuvant and adjuvant partial breast irradiation, whole breast, chest wall and regional nodal irradiation) are reviewed and their advantages as well as challenging aspects discussed.
Keywords
Adaptive radiotherapy, Breast cancer, MR-linac, Partial breast irradiation, Oncology, Radiology Nuclear Medicine and imaging, Review, Journal Article
Citation
De-Colle, C, Kirby, A, Russell, N, Shaitelman, S F, Currey, A, Donovan, E, Hahn, E, Han, K, Anandadas, C N, Mahmood, F, Lorenzen, E L, van den Bongard, D, Groot Koerkamp, M L, Houweling, A C, Nachbar, M, Thorwarth, D & Zips, D 2023, 'Adaptive radiotherapy for breast cancer', Clinical and translational radiation oncology, vol. 39, 100564. https://doi.org/10.1016/j.ctro.2022.100564