Non-invasive Angiographic-based Fractional Flow Reserve: Technical Development, Clinical Implications, and Future Perspectives
Publication date
2023-06
Authors
Peper, Joyce
Bots, Michiel L.
Leiner, Tim
Swaans, Martin J
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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License
cc_by
Abstract
New non- and less-invasive techniques have been developed to overcome the procedural and operator related burden of the fractional flow reserve (FFR) for the assessment of potentially significant stenosis in the coronary arteries. Virtual FFR-techniques can obviate the need for the additional flow or pressure wires as used for FFR measurements. This review provides an overview of the developments and validation of the virtual FFR-algorithms, states the challenges, discusses the upcoming clinical trials, and postulates the future role of virtual FFR in the clinical practice.
Keywords
Coronary Angiography/methods, Coronary Stenosis/diagnostic imaging, Coronary Vessels/diagnostic imaging, Fractional Flow Reserve, Myocardial, Humans, Predictive Value of Tests, coronary artery disease, diagnostic accuracy, quantitative flow ratio, physiology guided percutaneous coronary intervention, fractional flow reserve, Genetics, Biochemistry, Review, Journal Article
Citation
Peper, J, Bots, M L, Leiner, T & Swaans, M J 2023, 'Non-invasive Angiographic-based Fractional Flow Reserve : Technical Development, Clinical Implications, and Future Perspectives', Current medical science, vol. 43, no. 3, pp. 423-433. https://doi.org/10.1007/s11596-023-2751-4