Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer

Publication date

2022-10

Authors

Teunissen, F R
van der Voort van Zyp, Jochem R NISNI 0000000393775683
de Groot-van Breugel, Eline N
Verkooijen, Helena MORCID 0000-0001-9480-1623
Wortel, Ruud C
de Boer, Johannes C J

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Supervisors

Document Type

Article

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Abstract

Neurovascular bundle (NVB) and internal pudendal artery (IPA) sparing during magnetic resonance-guided radiotherapy (MRgRT) for prostate cancer aims for preservation of erectile function. Our present workflow involves daily online contouring and re-planning on a 1.5 T MR-linac, as alternative to conventional (rigid) translation-only corrections of the prostate. We compared planned dose for the NVB and IPA between strategies. Total planned dose was significantly lower with daily online contouring and re-planning for the NVB, but not for the IPA. For the NVB and IPA, the intrapatient difference between highest and lowest fraction dose was significantly smaller for the contouring and re-planning plans.

Keywords

Adapt-to-position, Adapt-to-shape, Localized prostate cancer, MR-Linac, MRgRT, Neurovascular-sparing, Radiation, Oncology, Radiology Nuclear Medicine and imaging, Journal Article

Citation

Teunissen, F R, van der Voort van Zyp, J R N, de Groot-van Breugel, E N, Verkooijen, H M, Wortel, R C & de Boer, J C J 2022, 'Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer', Physics and Imaging in Radiation Oncology, vol. 24, pp. 43-46. https://doi.org/10.1016/j.phro.2022.09.002