Retriever fetches integrins from endosomes

Publication date

2017-10-01

Authors

Rabouille, CISNI 0000000001502935

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Advisors

Supervisors

Document Type

Article

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taverne

Abstract

Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α 5 β 1 integrins.

Keywords

Taverne, Cell Biology

Citation

Rabouille, C 2017, 'Retriever fetches integrins from endosomes', Nature Cell Biology, vol. 19, no. 10, pp. 1144-1146. https://doi.org/10.1038/ncb3612