Modelling PM2.5 reduction scenarios for future cardiopulmonary disease reduction

Publication date

2026

Authors

Weber, EarthaISNI 000000051265878X
Daioglou, VassilisORCID 0000-0002-6028-352XISNI 0000000419508234
Vreedenburgh, Laszlo
Doelman, Jonathan C.ORCID 0000-0002-6842-573XISNI 0000000492496647
Downward, George SISNI 0000000505992966
Pinho, Maria GMORCID 0000-0003-4928-0851ISNI 0000000500911522
van Vuuren, Detlef P.ORCID 0000-0003-0398-2831ISNI 0000000040910093

Editors

Advisors

Supervisors

Document Type

Article
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License

taverne

Abstract

Long-term PM2.5 exposure is a risk factor for cardiovascular and respiratory mortality. Here a global health impact assessment was conducted utilizing seven future scenarios evaluating strategies to reduce PM2.5 exposure. Strategies included reducing fossil fuel use, air pollution control, adopting cleaner cooking methods and combinations thereof. Under current trends, air quality is projected to improve by 2050; nevertheless, the absolute attributable burden of ischaemic heart disease, stroke and chronic obstructive pulmonary disease remains high in many regions. Cleaner cooking fuel use is effective in the short term (by 2030) in South and Central America, Asia, and Africa for reducing PM2.5-related deaths. In the long term (by 2050) for most regions, only strategies that simultaneously target ambient and cooking-related PM2.5 resulted in sustained improvements that expand beyond current trends for reducing disease burden across these three health outcomes. In the Asian region, for example, under current trends, the population-attributable fraction decreases from 35% in 2015 to 18% in 2050. In the scenario combining universal clean cooking and climate policy, it drops further to 15%, and when all strategies are combined, it reaches as low as 11% by 2050. With all strategies combined, the average global population-weighted PM2.5 exposure from both ambient and cooking sources is reduced by nearly two-thirds (66 µg m−3 compared with 26 µg m−3). For North Africa and the Middle East region, the population-attributable fraction remains high across all scenarios. Additional strategies beyond those mentioned here are required to further improve air quality. It is recommended to pursue climate mitigation alongside universal access to cleaner household fuels to maximize cardiopulmonary health benefits.

Keywords

Taverne, Global and Planetary Change, Food Science, Geography, Planning and Development, Ecology, Renewable Energy, Sustainability and the Environment, Urban Studies, Nature and Landscape Conservation, Management, Monitoring, Policy and Law, SDG 13 - Climate Action

Citation

Weber, E, Daioglou, V, Vreedenburgh, L, Doelman, J, Downward, G, de Pinho, M G M & van Vuuren, D 2026, 'Modelling PM2.5 reduction scenarios for future cardiopulmonary disease reduction', Nature Sustainability, vol. 9, no. 1, pp. 77-85. https://doi.org/10.1038/s41893-025-01676-9