Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care
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Publication date
2015-08-01
Authors
de Vries-van Vugt, Saskia F.
Broekhuizen, Berna D L
Zuithoff, Nicolaas P.A.
van Essen, G.A.
Ebell, Mark H.
Coenen, Samuel
Ieven, Margareta
Lammens, Christine
Goossens, Herman
Butler, Chris C.
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Document Type
Article
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taverne
Abstract
Background. Valid clinical predictors of influenza in patients presenting with lower respiratory tract infection (LRTI) symptoms would provide adequate patient information and reassurance. Aim. Assessing the validity of an existing diagnostic model (Flu Score) to detect influenza in LRTI patients. Design and Setting. A European diagnostic study recruited 1801 adult primary care patients with LRTI-like symptoms existing ≤7 days between October and April 2007-2010. Method. History and physical examination findings were recorded and nasopharyngeal swabs taken. Polymerase chain reaction (PCR) for influenza A/B was performed as reference test. Diagnostic accuracy of the Flu Score (1× onset
Keywords
Cough, Diagnostic accuracy, Europe, Influenza, Lower respiratory tract infection, Primary health care, Taverne, Family Practice, Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't, Validation Studies
Citation
de Vries-van Vugt, S F, Broekhuizen, B D L, Zuithoff, N P A, van Essen, G A, Ebell, M H, Coenen, S, Ieven, M, Lammens, C, Goossens, H, Butler, C C, Hood, K, Littleg, P, Verheij, T J M, Zuithoff, P, van Essen, T, Almirall, J, Blasi, F, Chlabicz, S, Davies, M, Godycki-Cwirko, M, Hupkova, H, Kersnik, J, Mierzecki, A, Mölstad, S, Moore, M, Schaberg, T, de Sutter, A, Torres, A, Touboul, P, Little, P & Verheij, T 2015, 'Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care', Family Practice, vol. 32, no. 4, pp. 408-414. https://doi.org/10.1093/fampra/cmv039