Developmental trajectory of transmission speed in the human brain

Publication date

2023-04

Authors

van Blooijs, Dorien
van den Boom, Max A
van der Aar, Jaap F
Huiskamp, Geertjan MISNI 0000000389847234
Castegnaro, Giulio
Demuru, Matteo
Zweiphenning, Willemiek
van Eijsden, PieterISNI 0000000395119700
Miller, Kai J
Leijten, Frans S.ORCID 0000-0003-2603-3364ISNI 0000000396446949

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Document Type

Article

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cc_by

Abstract

The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.

Keywords

General Neuroscience, Journal Article

Citation

van Blooijs, D, van den Boom, M A, van der Aar, J F, Huiskamp, G M, Castegnaro, G, Demuru, M, Zweiphenning, W J E M, van Eijsden, P, Miller, K J, Leijten, F S S & Hermes, D 2023, 'Developmental trajectory of transmission speed in the human brain', Nature Neuroscience, vol. 26, no. 4, pp. 537-541. https://doi.org/10.1038/s41593-023-01272-0