Patient preferences and attitudes regarding the environmental impact of medicines: A discrete choice experiment

Publication date

2025-10

Authors

Sadreghaemy, Milad
Philbert, DaphneISNI 0000000390943506
Heerdink, RobORCID 0000-0002-5946-7209ISNI 0000000394315283
Bouvy, MarcelISNI 0000000055088944
Egberts, ToineORCID 0000-0003-1758-7779ISNI 0000000392745722
Bloem, Lourens T.ORCID 0000-0002-0014-8625ISNI 000000049260699X

Editors

Advisors

Supervisors

Document Type

Article
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License

cc_by_nc

Abstract

AIMS: Pharmaceutical utilization within global healthcare has significant environmental impact throughout its lifecycle. Understanding how the environmental impact of medicines influences patients' preferences relative to ease of use and cost supports interventions promoting appropriate medicine consumption, reduced waste and environmental sustainability. The aim of this study was to investigate patient preferences and attitudes regarding the environmental impact of medicines in relation to ease of use and cost. METHODS: A cross-sectional survey (December 2022 to January 2023) was conducted using the Dutch AMP pharmacy panel (>25 000 chronic medicine users). It included a discrete choice experiment (DCE) on medicines' environmental impact, ease of use and cost, and questions on environmental sustainability in medicine use and daily life. Latent class analysis identified groups with shared preferences. An environmental sustainability attitude score was calculated from daily life behaviour. RESULTS: Of 25 787 invited panel members 6390 responded and 4122 were included in the analysis (16.0%, mean age 68 years, 42.6% female). Four preference groups were identified and labelled based on DCE-derived attribute preferences: eco-focused (55.7%), cost-focused (20.1%), indifferent (16.4%) and eco-sceptical (7.8%). Environmental sustainability attitude scores were highest in the eco-focused and eco-sceptical (median 75.0%) groups, followed by the indifferent and cost-focused (median 66.7%) groups. Important factors influencing this were environmental concerns (eco-focused), environmental and personal health concerns (eco-sceptical), costs (cost-focused) and environmental, cost and personal health concerns (indifferent). Only 8.8-15.5% reported good or very good self-assessed knowledge of medicines' environmental impact. CONCLUSIONS: Environmental sustainability significantly affects medicine preferences, although heterogeneity exists. Tailored initiatives are required to promote environmentally sustainable pharmaceutical care.

Keywords

discrete choice experiment, environmental impact, medicine waste, patient preferences, pharmaceutical care, sustainable medicine use, sustainable pharmacy, Pharmacology, Pharmacology (medical)

Citation

Sadreghaemy, M, Philbert, D, Heerdink, E R, Bouvy, M L, Egberts, T C G & Bloem, L T 2025, 'Patient preferences and attitudes regarding the environmental impact of medicines : A discrete choice experiment', British Journal of Clinical Pharmacology, vol. 91, no. 10, pp. 2771-2781. https://doi.org/10.1002/bcp.70244