Comment on the article by Trolese T et al

Abstract

The recent introduction of quadripolar leads for cardiac resynchronization therapy raises the question which pacing vector is most beneficial to response and which parameter gives insight into the optimal vector. The study conducted by Trolese et al. is therefore of important value and unique in its kind.1 The found correlation between maximal difference of the QRS-width (ΔQRS) and acute haemodynamic response (AHR) (ΔLV dP/dtmax) is an important finding to aid vector selection. However, their results give rise to questions.