Visuospatial Functioning in Cerebral Amyloid Angiopathy: A Pilot Study
Publication date
2017
Authors
Valenti, Raffaella
Charidimou, Andreas
Xiong, Li
Boulouis, Gregoire
Fotiadis, Panagiotis
Ayres, Alison
Riley, Grace
Kuijf, Hugo J.
Reijmer, Yael D.
Pantoni, Leonardo
Editors
Advisors
Supervisors
Document Type
Article
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taverne
Abstract
Cerebral amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly. We hypothesized that the posterior cortical predilection of CAA would cause visual-processing impairment. We systematically evaluated visuospatial abilities in 22 non-demented CAA patients. Neurocognitive evaluation demonstrated visuoperceptual impairment (23 on Benton Facial Recognition Test [BFRT] and 13.6 on Benton Judgment of Line Orientation Test [BJLO]). BFRT was inversely correlated with white matter hyperintensities volume and BJLO with parietal cerebral microbleeds. This pilot study highlights the presence of visual-processing deficits in CAA. The impairment could be related to global disease severity in addition to local brain injury.
Keywords
Cerebral amyloid angiopathy, Neuroimaging markers, Neuropsychological assessment, Visuospatial functioning, Taverne, Clinical Psychology, Geriatrics and Gerontology, Psychiatry and Mental health, Journal Article
Citation
Valenti, R, Charidimou, A, Xiong, L, Boulouis, G, Fotiadis, P, Ayres, A, Riley, G, Kuijf, H J, Reijmer, Y D, Pantoni, L, Gurol, M E, Davidsdottir, S, Greenberg, S M & Viswanathan, A 2017, 'Visuospatial Functioning in Cerebral Amyloid Angiopathy : A Pilot Study', Journal of Alzheimer's Disease, vol. 56, no. 4, pp. 1223-1227. https://doi.org/10.3233/JAD-160927