Beam characterisation of the 1.5 T MRI-linac

Publication date

2018-04-19

Authors

Woodings, Simon J
Bluemink, Johanna J.
de Vries, J H Wilfred
Niatsetski, Yury
van Veelen, Bob
Schillings, Joost
Kok, J. G MISNI 0000000391574140
Wolthaus, JWHISNI 0000000395891207
Hackett, Sara L
van Asselen, BISNI 0000000391220676

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Article

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taverne

Abstract

As a prerequisite for clinical treatments it was necessary to characterize the Elekta 1.5 T MRI-linac 7 MV FFF radiation beam. Following acceptance testing, beam characterization data were acquired with Semiflex 3D (PTW 31021), microDiamond (PTW 60019), and Farmer-type (PTW 30013 and IBA FC65-G) detectors in an Elekta 3D scanning water phantom and a PTW 1D water phantom. EBT3 Gafchromic film and ion chamber measurements in a buildup cap were also used. Special consideration was given to scan offsets, detector effective points of measurement and avoiding air gaps. Machine performance has been verified and the system satisfied the relevant beam requirements of IEC60976. Beam data were acquired for field sizes between 1  ×  1 and 57  ×  22 cm 2. New techniques were developed to measure percentage depth dose (PDD) curves including the electron return effect at beam exit, which exhibits an electron-type practical range of 1.2 ± 0.1 cm. The Lorentz force acting on the secondary charged particles creates an asymmetry in the crossline profiles with an average shift of  +0.24 cm. For a 10  ×  10 cm 2 beam, scatter from the cryostat contributes 1% of the dose at isocentre. This affects the relative output factors, scatter factors and beam profiles, both in-field and out-of-field. The average 20%-80% penumbral width measured for small fields with a microDiamond detector at 10 cm depth is 0.50 cm. MRI-linac penumbral widths are very similar to that of the Elekta Agility linac MLC, as is the near-surface dose PDD(0.2 cm)  =  57%. The entrance surface dose is  ∼36% of Dmax. Cryostat transmission is quantified for inclusion within the treatment planning system. As a result, the 1.5 T MRI-linac 7 MV FFF beam has been characterised for the first time and is suitable for clinical use. This was a key step towards the first clinical treatments with the MRI-linac, which were delivered at University Medical Center Utrecht in May 2017 (Raaymakers et al 2017 Phys. Med. Biol. 62 L41-50).

Keywords

radiotherapy, MRI-linac, dosimetry, unity, beam characterisation, commissioning, beam characterization, Water, Patient Positioning, Humans, Magnetic Resonance Imaging/methods, Magnetic Fields, Phantoms, Imaging, Particle Accelerators, Electrons, Radiometry/methods, Taverne, Radiological and Ultrasound Technology, Radiology Nuclear Medicine and imaging, Journal Article

Citation

Woodings, S J, Bluemink, J J, de Vries, J H W, Niatsetski, Y, van Veelen, B, Schillings, J, Kok, J G M, Wolthaus, J W H, Hackett, S L, van Asselen, B, van Zijp, H M, Pencea, S, Roberts, D A, Lagendijk, J J W & Raaymakers, B W 2018, 'Beam characterisation of the 1.5 T MRI-linac', Physics in Medicine and Biology, vol. 63, no. 8, 085015. https://doi.org/10.1088/1361-6560/aab566