Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

Publication date

2019

Authors

Blokland, S L M
Hillen, Maarten R.
Wichers, Catharina G. K.
Zimmermann, Maili
Kruize, AAISNI 0000000388353398
Radstake, Timothy R D JISNI 0000000382903168
Broen, Jasper C AISNI 0000000392193091
Van Roon, J. A GISNI 0000000390928883

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Document Type

Article

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Abstract

Keywords

B cells, Sjögren's syndrome, T cells, mTOR, rapamycin, Immunology and Allergy, Rheumatology, Immunology

Citation

Blokland, S L M, Hillen, M R, Wichers, C G K, Zimmermann, M, Kruize, A A, Radstake, T R D J, Broen, J C A & van Roon, J A G 2019, 'Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome : mTOR inhibition as a novel therapeutic strategy to halt immunopathology?', RMD Open, vol. 5, no. 1, e000701. https://doi.org/10.1136/rmdopen-2018-000701