KPC-like carbapenemase-producing enterobacteriaceae colonizing patients in Europe and Israel
Files
Publication date
2016-03-01
Authors
Baraniak, A.
Izdebski, R.
Fiett, J.
Herda, M.
Derde, Lennie P G
Bonten, Marc
Adler, A.
Carmeli, Y.
Goossens, H.
Hryniewicz, W.
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
Abstract
In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.
Keywords
Pharmacology, Infectious Diseases, Pharmacology (medical), Journal Article, Research Support, Non-U.S. Gov't
Citation
Baraniak, A, Izdebski, R, Fiett, J, Herda, M, Derde, L P G, Bonten, M J M, Adler, A, Carmeli, Y, Goossens, H, Hryniewicz, W, Brun-Buisson, C & Gniadkowski, M 2016, 'KPC-like carbapenemase-producing enterobacteriaceae colonizing patients in Europe and Israel', Antimicrobial Agents and Chemotherapy, vol. 60, no. 3, pp. 1912-1917. https://doi.org/10.1128/AAC.02756-15