At risk, or not at risk: Epidemiological approaches for assessing psychiatric (genetic) risk factors in the general population

Abstract

This thesis “At risk, or not at risk” describes several approaches - cross-sectional, prospective, phenotype mining and forward genetics - for assessing psychiatric (genetic) risk factors in a general population study. The aims were 1) to investigate how routine and follow-up data from populationbased studies can be used for investigating associations of psychiatric traits with (genetic) risk factors, and 2) to evaluate the additional value of a nested study with extensive psychiatric assessments within such a population study.