Endocrine Health in Childhood Cancer Survivors
Publication date
2020-12
Authors
Van Santen, Hanneke M.
Chemaitilly, Wassim
Meacham, Lillian R
Tonorezos, Emily S
Mostoufi-Moab, Sogol
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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License
cc_by
Abstract
Endocrine late effects, including reproductive disorders and secondary thyroid cancer, have been reported in up to 50 %childhood cancer survivors (CCS) more than 5 years after treatment. Most endocrine disorders are amenable to treatment; awareness of symptoms is therefore of great importance. Recognition of these symptoms may be delayed however because many are nonspecific. Timely treatment of endocrine disorders improves quality of life in CCS and prevents possible consequences, such as short stature, bone and cardiovascular disorders, and depression. At-risk CCS must therefore be regularly and systematically monitored. This article provides a summary of the most commonly reported endocrine late effects in CCS.
Keywords
Bone health, Childhood cancer survivor, Growth hormone deficiency, Hypothyroidism, Late effects, Metabolic syndrome, Radiation effects, Secondary thyroid cancer, Pediatrics, Perinatology, and Child Health
Citation
van Santen, H M, Chemaitilly, W, Meacham, L R, Tonorezos, E S & Mostoufi-Moab, S 2020, 'Endocrine Health in Childhood Cancer Survivors', The pediatric clinics of North America, vol. 67, no. 6, pp. 1171-1186. https://doi.org/10.1016/j.pcl.2020.08.002