From “synthetic” to defined microbial communities for clearer terminology

Publication date

2026-12

Authors

Koch, Hanna
Clavel, Thomas
Mayr, Cintia
Coltman, Benjamin L.
Schloter, Michael
Vorholt, Julia A.
Sanz, Yolanda
Cernava, Tomislav
Beattie, Gwyn A.
Lange, Lene

Editors

Advisors

Supervisors

Document Type

Comment
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License

cc_by

Abstract

Consortia of microbial isolates, also known as synthetic communities (SynComs), are increasingly used to study and harness microbe-microbe and microbe-host interactions. Since “synthetic” potentially evokes negative connotations, we propose adopting the term “Defined Microbial Community” for practical applications.

Keywords

General Chemistry, General Biochemistry,Genetics and Molecular Biology, General, General Physics and Astronomy

Citation

Koch, H, Clavel, T, Mayr, C, Coltman, B L, Schloter, M, Vorholt, J A, Sanz, Y, Cernava, T, Beattie, G A, Lange, L, Chaillou, S, Kovács, Á T, Smidt, H, Pieterse, C M J, Kostic, T, Finkel, O M, Lawson, C E, Cocolin, L, Mercado-Blanco, J, Finn, R D, Papadopoulou, K K, Ryan, M, Candela, M, Cotter, P D, Berg, G, O’Sullivan, O, Delgado-Baquerizo, M, Trivedi, P, Charles, T C, Singh, B K, Brader, G, Marian, M & Sessitsch, A 2026, 'From “synthetic” to defined microbial communities for clearer terminology', Nature Communications, vol. 17, no. 1, 5283, pp. 1-4. https://doi.org/10.1038/s41467-026-74251-1