Factors Associated With Glaucoma Surgery in Pediatric Non-Infectious Uveitis
Publication date
2023-12
Authors
van Meerwijk, Charlotte
Wieringa, Wietse G.
de Boer, Joke
Jansonius, Nomdo M.
Los, Leonoor I.
Editors
Advisors
Supervisors
Document Type
Article
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Abstract
Purpose: To identify factors associated with glaucoma surgery in pediatric uveitis. Methods: Patients diagnosed with uveitis before their 18th birthday and with an observation period of at least one year were included in a retrospective case-control study. Results: A total of 185 patients were included, 84 of whom had undergone glaucoma surgery. Juvenile idiopathic arthritis (JIA)-related uveitis was associated with undergoing glaucoma surgery (p = .002). In the JIA-subgroup, the presence of anterior segment complications (OR 3.1 (95% CI 1.0 to 9.6); P = .045) and an IOP > 21 mmHg during the first uveitis remission (OR 4.5 (95% CI 1.3 to 15.2); P = .015) were associated with an increased risk of glaucoma surgery. Sixty-eight percent of the cases needed glaucoma surgery within one year after they started IOP-lowering triple therapy. Conclusion: The risk profile for undergoing glaucoma surgery as outlined in this study is a valuable help to recognize and treat secondary glaucoma in a timely manner.
Keywords
Glaucoma, pediatrics, risk factors, surgery, uveitis, Immunology and Allergy, Ophthalmology
Citation
van Meerwijk, Wieringa, W G, de Boer, J H, Jansonius, N M & Los, L I 2023, 'Factors Associated With Glaucoma Surgery in Pediatric Non-Infectious Uveitis', Ocular Immunology and Inflammation, vol. 31, no. 10, pp. 2018-2023. https://doi.org/10.1080/09273948.2023.2166849