Respiratory Pathogen Detection in Children: Saliva as a Diagnostic Specimen
Publication date
2021-09
Authors
de Koff, Emma M.
Euser, Sjoerd M.
Badoux, Paul
Sluiter-Post, Judith
Eggink, Dirk
Sanders, Elisabeth A M
van Houten, Marlies A.
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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License
taverne
Abstract
We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or sponges, 94% (95% CI: 74%-99%). Saliva could be a relevant specimen alternative.
Keywords
diagnostics, pediatrics, respiratory pathogens, saliva, Taverne, Pediatrics, Perinatology, and Child Health, Microbiology (medical), Infectious Diseases
Citation
De Koff, E M, Euser, S M, Badoux, P, Sluiter-Post, J, Eggink, D, Sanders, E A M & Van Houten, M A 2021, 'Respiratory Pathogen Detection in Children : Saliva as a Diagnostic Specimen', Pediatric Infectious Disease Journal, vol. 40, no. 9, pp. E351-E353. https://doi.org/10.1097/INF.0000000000003191