European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma. Part 1: Diagnostics and prevention–Update 2023
Publication date
2023-11
Authors
Stratigos, Alexander J.
Garbe, Claus
Dessinioti, Clio
Lebbe, Celeste
van Akkooi, Alexander
Bataille, Veronique
Bastholt, Lars
Dreno, Brigitte
Dummer, Reinhard
Fargnoli, Maria Concetta
Editors
Advisors
Supervisors
Document Type
Article
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cc_by_nc_nd
Abstract
Invasive cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in white populations, accounting for 20% of all cutaneous malignancies. Overall, cSCC mostly has very good prognosis after treatment, with 5-year cure rates greater than 90%. Despite the overall favourable prognosis and the proportionally rare deaths, cSCC is associated with a high total number of deaths due to its high incidence. A collaboration of multidisciplinary experts from the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), the European Society for Radiotherapy and Oncology (ESTRO), the European Union of Medical Specialists (UEMS), the European Academy of Dermatology and Venereology (EADV) and the European Organization of Research and Treatment of Cancer (EORTC), was formed to update recommendations on cSCC, based on current literature and expert consensus. Part 1 of the guidelines addresses the updates on classification, epidemiology, diagnosis, risk stratification, staging and prevention in immunocompetent as well as immunosuppressed patients.
Keywords
Advanced, Diagnosis, High-risk, Immunosuppression, Invasive cutaneous squamous cell carcinoma, Locally advanced cSCC, Metastatic cSCC, Prevention, Prognosis, Staging, Oncology, Cancer Research
Citation
Stratigos, A J, Garbe, C, Dessinioti, C, Lebbe, C, van Akkooi, A, Bataille, V, Bastholt, L, Dreno, B, Dummer, R, Fargnoli, M C, Forsea, A M, Harwood, C A, Hauschild, A, Hoeller, C, Kandolf-Sekulovic, L, Kaufmann, R, Kelleners-Smeets, N WJ, Lallas, A, Leiter, U, Malvehy, J, del Marmol, V, Moreno-Ramirez, D, Pellacani, G, Peris, K, Saiag, P, Tagliaferri, L, Trakatelli, M, Ioannides, D, Vieira, R, Zalaudek, I, Arenberger, P, Eggermont, A M M, Röcken, M, Grob, J J, Lorigan, P & On behalf of EADO, EDF, ESTRO, UEMS, EADV and EORTC 2023, 'European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma. Part 1 : Diagnostics and prevention–Update 2023', European Journal of Cancer, vol. 193, 113251. https://doi.org/10.1016/j.ejca.2023.113251