Double-blind, placebo-controlled study of the efficacy of nandrolone laurate in the treatment of dobermanns with subclinical hepatitis
Publication date
2005-09-10
Authors
Mandigers, Paul J J
Horspool, L J L
van den Ingh, T S G A M
Teske, E
Bode, P
Rothuizen, Jan
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DOI
Document Type
Article
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Abstract
Twenty-one three-year-old dobermanns with subclinical hepatitis were treated with nandrolone laurate or a placebo in a double-blind trial. The dogs were scored clinically before and after four months of treatment and they were evaluated by clinical biochemistry and liver biopsies. After the treatment no significant differences were observed between the two groups in any of the clinical biochemistry values; eight of the 21 dogs had no histological evidence of hepatitis and five other dogs had improved, but there was no significant difference between the responses of the two groups.
Keywords
Androgens, Animals, Dog Diseases, Dogs, Double-Blind Method, Female, Hepatitis, Animal, Liver, Male, Nandrolone, Placebos, Treatment Outcome, SDG 3 - Good Health and Well-being
Citation
Mandigers, P J J, Horspool, L J L, van den Ingh, T S G A M, Teske, E, Bode, P & Rothuizen, J 2005, 'Double-blind, placebo-controlled study of the efficacy of nandrolone laurate in the treatment of dobermanns with subclinical hepatitis', Veterinary Record, vol. 157, no. 11, pp. 313-317.