Immunoglobulin determination evaluation of the results of immunoelectrophoretic analysis and the radial diffusion method

Abstract

A comparative study was made of the results of immunoglobulin determination in sera using immunoelectrophoresis and the radial diffusion method of Mancini. The results indicated that, except for certain ranges of immunoglobulin concentration (low, normal or slightly increased) the data obtained by immunoelectrophoresis are unreliable and do not correlate with the values obtained by the Mancini method.