A quarter of admitted poisoned patients have a mild poisoning and require no treatment: An observational study

Publication date

2019-08-01

Authors

Hondebrink, LauraORCID 0000-0001-9823-008XISNI 0000000396548435
Rietjens, Saskia JISNI 0000000388052595
Donker, D W
Hunault, Claudine CORCID 0000-0001-7843-6208ISNI 0000000396049679
van den Hengel-Koot, Irma
Verputten, Pauline M.
de Vries, Irma
Kaasjager, Karin A HISNI 0000000394886959
Dekker, DouweISNI 0000000396416926
de Lange, Dylan WORCID 0000-0002-0191-7270

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Article

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taverne

Abstract

Background: Poisoned patients are frequently admitted following Emergency Department (ED) presentation, while the necessity of such admissions is hardly investigated. We determined the proportion and characteristics of poisoned patients who were admitted, but in retrospect had an uneventful admission. Methods: For this observational cohort study, all patients presented to the ED of a Dutch University Hospital with various poisonings during a 1.5-year period (January 2015–July 2016) were included. The uneventfulness of admissions, defined as patients with a low Poisoning Severity Score (PSS) who received no treatment, was determined in retrospect. Results: We included 417 patients who visited the ED for poisoning. 247 Patients were admitted: 30% to a general ward, 58% to a MCU, and 12% to the ICU. The poisoning severity scores of the admitted patients were none to mild in 38%, moderate to severe in 59%, and fatal in 2%. Upon admission, 60% of the patients received treatment. In retrospect, 77% of the admitted patients had a moderate, severe or fatal poisoning and/or required treatment. However, 23% of the admitted patients had a mild poisoning and required no treatment. This group involved younger patients (median age of 23 versus 42 years) and a higher proportion of patients reporting exposure to only one substance (65% versus 51%). Conclusions: The majority of poisoned patients presented to the ED was admitted, while in retrospect, a quarter of these admissions were uneventful. Predictive parameters should be sought to identify patients who can be sent home safely.

Keywords

Emergency department, Intoxication, Outcome, Poisoning severity score, Taverne, Internal Medicine, Journal Article

Citation

Hondebrink, L, Rietjens, S J, Donker, D W, Hunault, C C, van den Hengel-Koot, I, Verputten, P M, de Vries, I, Kaasjager, K A H, Dekker, D & de Lange, D W 2019, 'A quarter of admitted poisoned patients have a mild poisoning and require no treatment : An observational study', European journal of internal medicine, vol. 66, pp. 41-47. https://doi.org/10.1016/j.ejim.2019.05.012