Combined therapy for thyroid squamous cell carcinoma
Publication date
2012-01
Authors
de Vos, Filip Y F L
Sewnaik, Aniel
de Wilt, J Hans W
Smid, Ernst J
den Bakker, Michael A
van Meerten, Esther
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Supervisors
Document Type
Article
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Abstract
BACKGROUND.: Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis. METHODS AND RESULTS.: We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy. CONCLUSIONS.: Our patient now has a recurrence-free survival of >20 months, longer than the mean survival described in the literature.
Keywords
Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Squamous Cell, Cisplatin, Combined Modality Therapy, Female, Humans, Induction Chemotherapy, Middle Aged, Paclitaxel, Thyroid Neoplasms, Case Reports, Journal Article
Citation
De Vos, F Y F L, Sewnaik, A, de Wilt, J H W, Smid, E J, den Bakker, M A & van Meerten, E 2012, 'Combined therapy for thyroid squamous cell carcinoma', Head and Neck, vol. 34, no. 1, pp. 131-134. https://doi.org/10.1002/hed.21484