In vitro human cell-based models: What can they do and what are their limitations?

Publication date

2024-08-22

Authors

Lutolf, Matthias P.
Radisic, Milica
Beekman, Jeffrey M.ISNI 0000000388915338
Huh, Dan Dongeun
Huch, Meritxell
Turco, Margherita Yayoi
Birgani, Zeinab Niloofar Tahmasebi
Gao, Dong
Yao, Rui
Lin, Hang

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taverne

Abstract

It is said that all models are wrong, but some are useful. In vitro human cell-based models are a prime example of this maxim. We asked researchers: when is your model system useful? How can it be made more useful? What are its limitations?

Keywords

Taverne, Biotechnology, Bioengineering

Citation

Lutolf, M P, Radisic, M, Beekman, J, Huh, D D, Huch, M, Turco, M Y, Birgani, Z N T, Gao, D, Yao, R, Lin, H & Takebe, T 2024, 'In vitro human cell-based models : What can they do and what are their limitations?', Trends in biotechnology, vol. 42, no. 12, pp. 1577-1582. https://doi.org/10.1016/j.tibtech.2024.08.015