Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation

Publication date

2019-12-16

Authors

Fréal, AmélieISNI 0000000430677047
Hoogenraad, Casper C.ISNI 0000000396512854

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Article
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taverne

Abstract

Local microtubule remodeling plays a crucial role in controlling the transport of neuronal cargo. A new study reveals that excitatory en passant boutons in the axon are hotspots for activity-induced microtubule nucleation and provide tracks for interbouton vesicle trafficking.

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Citation

Freal, A & Hoogenraad, C C 2019, 'Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation', Current Biology, vol. 29, no. 24, pp. R1307-R1309. https://doi.org/10.1016/j.cub.2019.11.011