Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT
Publication date
2017-12-01
Authors
Adams, Hugo J A
de Klerk, John M. H.
Regelink, Josien C.
Heggelman, Ben G. F.
Dubois, Stefan V.
Kwee, Thomas C.
Editors
Advisors
Supervisors
Document Type
Article
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taverne
Abstract
A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A complete metabolic remission was achieved after two cycles of ABVD, which was maintained until three years after completion of treatment. Follow-up FDG-PET/CT four years after completion of treatment, however, showed a new FDG-avid (Deauville score of 4) lesion in the right scapula, suggesting relapsed disease. Computer tomography (CT)-guided biopsy of this lesion was performed and subsequent histological examination revealed a radiation-induced giant cell granuloma.
Keywords
Biopsy, FDG-PET/CT, Giant cell granuloma, Hodgkin lymphoma, Taverne, Radiology Nuclear Medicine and imaging, Journal Article
Citation
Adams, H J A, de Klerk, J M H, Regelink, J C, Heggelman, B G F, Dubois, S V & Kwee, T C 2017, 'Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT', Nuclear Medicine and Molecular Imaging, vol. 51, no. 4, pp. 371-373. https://doi.org/10.1007/s13139-016-0426-9