Pathology of intraductal papillary mucinous neoplasms

Publication date

2021-12

Authors

Assarzadegan, Naziheh
Thompson, Elizabeth
Salimian, Kevan
Gaida, Matthias M
Brosens, Lodewijk AORCID 0000-0003-1341-8994
Wood, Laura
Ali, Syed Z
Hruban, Ralph H

Editors

Advisors

Supervisors

Document Type

Article

Collections

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License

taverne

Abstract

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient. PURPOSE: Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions. CONCLUSIONS: Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.

Keywords

Intraductal oncocytic papillary neoplasm, Intraductal papillary mucinous neoplasm, Intraductal tubulopapillary neoplasm, Pancreas cancer, Pancreatic cancer, Pathology, Taverne, Surgery, Journal Article

Citation

Assarzadegan, N, Thompson, E, Salimian, K, Gaida, M M, Brosens, L A A, Wood, L, Ali, S Z & Hruban, R H 2021, 'Pathology of intraductal papillary mucinous neoplasms', Langenbeck's Archives of Surgery, vol. 406, no. 8, pp. 2643-2655. https://doi.org/10.1007/s00423-021-02201-0