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Cu(I)- and Ru(II)-mediated "click" cyclization of tripeptides toward vancomycin-inspired mimics

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Publication date

2011-07-01

Authors

Zhang, Jinqiang
Kemmink, JohanISNI 0000000396412255
Rijkers, D.T.S.ISNI 0000000390501855
Liskamp, RobISNI 0000000393845493

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DOI

https://doi.org/10.1021/ol201184b

Document Type

Article

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Abstract

Structural mimics comprising 1,4- and 1,5-disubstituted triazole-containing cyclic tripeptides with excellent resemblance toward the DE-ring of vancomycin are conveniently accessible using Cu(I)- or Ru(II)-assisted "click" cyclization. © 2011 American Chemical Society.

Keywords

copper, drug derivative, peptide, ruthenium, vancomycin, article, catalysis, chemical structure, chemistry, cyclization, synthesis

Citation

Zhang, J, Kemmink, J, Rijkers, D T S & Liskamp, R M J 2011, 'Cu(I)- and Ru(II)-mediated "click" cyclization of tripeptides toward vancomycin-inspired mimics', Organic Letters, vol. 13, no. 13, pp. 3438-3441. https://doi.org/10.1021/ol201184b

URI

https://dspace.library.uu.nl/handle/1874/468820