Tipping the spindle into the right position
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Publication date
2016
Authors
Akhmanova, Anna
van den Heuvel, Sander
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Abstract
The position of the mitotic spindle determines the cleavage plane in animal cells, but what controls spindle positioning? Kern et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510117) demonstrate that the microtubule plus end-associated SKAP/Astrin complex participates in this process, possibly by affecting dynein-dependent pulling forces exerted on the tips of astral microtubules.
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Akhmanova, A & van den Heuvel, S 2016, 'Tipping the spindle into the right position', Journal of Cell Biology, vol. 213, no. 3, pp. 293-5. https://doi.org/10.1083/jcb.201604075