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Artificial Metalloenzymes for Hydrogenation and Transfer Hydrogenation Reactions

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basauri_molina.pdf (1.14 MB)

Publication date

2018-03-25

Authors

Basauri Molina, ManuelISNI 000000039503191X
Klein Gebbink, R.J.M.ISNI 0000000388707889

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DOI

https://doi.org/10.1002/9783527804085.ch6

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Part of book

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taverne

Abstract

The development of artificial hydrogenases (AHases) and transfer hydrogenases (ATHases) has played a leading and guiding role for the field of artificial metalloenzymes. Starting from the early studies by Whitesides and coworkers, this chapter showcases the conceptual development of AHases and ATHases, highlighting the different conjugation strategies used for their construction and exemplifying the stereoselective control in product formation that can be reached.

Keywords

artificial metalloenzymes, catalytic hydrogenation, transfer hydrogenation, directed evolution, enantioselectivity, rhodium, ruthenium, iridium, Taverne

Citation

Basauri-molina, M & Gebbink, R J M K 2018, Artificial Metalloenzymes for Hydrogenation and Transfer Hydrogenation Reactions. in Artificial Metalloenzymes and MetalloDNAzymes in Catalysis : From Design to Applications. Wiley, pp. 171-197. https://doi.org/10.1002/9783527804085.ch6

URI

https://dspace.library.uu.nl/handle/1874/375615