Extracorporele life support bij Legionella-pneumonie

Abstract

BACKGROUND: Legionella species cause 5% of all community acquired pneumonias. However, Legionella pneumonia results relatively often in admission to the intensive care unit (ICU). A significant complication is the development of acute respiratory distress syndrome (ARDS). The ICU mortality rate for Legionella pneumonia is > 30% with conventional treatments. CASE DESCRIPTION: A 64-year-old male was admitted to the ICU with respiratory failure due to Legionella pneumonia complicated by ARDS. Despite maximum conventional therapy being given, including lung-protective invasive mechanical ventilation and prone positioning, progressive hypoxaemia persisted. In collaboration with an extracorporeal life support (ECLS) centre, venovenous ECLS was initiated. Pulmonary function recovered and the patient was successfully weaned from VV-ECLS after 17 days. After three months of hospitalisation and rehabilitation, the patient was discharged home and able to perform his activities of daily living without assistance. CONCLUSION: Legionella pneumonia relatively frequently results in ICU admission, and carries a high mortality with conventional treatments. ECLS may offer a solution if conventional therapies are not sufficiently effective.