CFTR and colorectal cancer susceptibility: an urgent need for further studies
Publication date
2024-10
Authors
Spelier, S
Derksen, S
Hofland, Regina W.
Beekman, JM
Yetkin-Arik, Bahar
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
No license information available
Abstract
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene result in cystic fibrosis, a multiorgan disease characterized by aberrant epithelial cell fluid secretion. Recent studies describe a connection between CFTR malfunctioning and a heightened susceptibility to colorectal cancer (CRC). Here, we outline these links and suggest directions for further studies.
Keywords
Oncology, Cancer Research, Journal Article
Citation
Spelier, S, Derksen, S, Hofland, R, Beekman, J M & Yetkin-Arik, B 2024, 'CFTR and colorectal cancer susceptibility : an urgent need for further studies', Trends in Cancer, vol. 10, no. 10, pp. 876-879. https://doi.org/10.1016/j.trecan.2024.07.006