Fast and accurate deformable contour propagation for intra-fraction adaptive magnetic resonance-guided prostate radiotherapy
Publication date
2022-01
Authors
Willigenburg, Thomas
Zachiu, Cornel
Lagendijk, J J W
van der Voort van Zyp, Jochem R N
de Boer, Johannes C J
Raaymakers, Bas W
Editors
Advisors
Supervisors
Document Type
Article
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Abstract
To facilitate full intra-fraction adaptive MR-guided radiotherapy, accurate contour propagation is needed. We aimed to assess the clinical usability of intra-fraction propagated contours by a deformable image registration algorithm in ten prostate cancer patients. Two observers judged the contours on need for manual adaptation and feasibility of adapting contours within 3 min. CTV and bladder contours needed none or only minor editing in most cases (≥ 97%), whereas rectum contours needed more extensive editing in 12-23%. Nevertheless, adaptation times were < 3 min for ≥ 93% of the cases. This paves the way for exploring adaptive workflows using intra-fraction deformable contour propagation.
Keywords
Intra-fraction adaptation, MR-guided linear accelerator, MRI-guided radiotherapy, Prostate cancer, Radiotherapy workflow, Radiation, Oncology, Radiology Nuclear Medicine and imaging, Journal Article
Citation
Willigenburg, T, Zachiu, C, Lagendijk, J J W, van der Voort van Zyp, J R N, de Boer, H C J & Raaymakers, B W 2022, 'Fast and accurate deformable contour propagation for intra-fraction adaptive magnetic resonance-guided prostate radiotherapy', Physics and Imaging in Radiation Oncology, vol. 21, pp. 62-65. https://doi.org/10.1016/j.phro.2022.02.008