Prolonged Grief, Depressive, and Posttraumatic Stress Symptoms: Random-Intercept Cross-Lagged Panel Analyses

Publication date

2026-03

Authors

Janshen, Antje
Boelen, PaulISNI 000000004342164X
Huisman, Mark
Eisma, Maarten C.ISNI 0000000419435653

Editors

Advisors

Supervisors

Document Type

Article
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License

cc_by

Abstract

Prolonged grief symptoms often co-occur with depressive and posttraumatic stress (PTS) symptoms, but the temporal relationships between prolonged grief symptoms and other postloss psychopathology symptoms are not well understood. Insights into the temporal relationships can inform treatment decisions for bereaved adults. Therefore, we aimed to clarify these temporal relationships. Three-hundred seven bereaved adults within their first bereavement year (78% female) completed questionnaires to assess prolonged grief, depressive, and PTS symptoms at five time points at 1.5-month intervals. Random-intercept cross-lagged panel modeling was utilized to inspect reciprocal relationships between these symptoms. Higher prolonged grief symptoms than usual predicted other psychopathology symptoms and vice versa across at least one interval in all bivariate models. In a model including prolonged grief, depressive, and PTS symptoms, within-person fluctuations in acute grief (i.e., grief occurring between 0 and 6 months after loss) levels predicted other postloss symptoms but not vice versa. Most variance could be attributed to stable differences between individuals. Future research should examine the clinical utility of targeting acute grief reactions to prevent the emergence of other postloss psychopathology.

Keywords

comorbidity, longitudinal, major depressive disorder, posttraumatic stress disorder, prolonged grief disorder, Clinical Psychology

Citation

Janshen, A, Boelen, P A, Huisman, M & Eisma, M C 2026, 'Prolonged Grief, Depressive, and Posttraumatic Stress Symptoms : Random-Intercept Cross-Lagged Panel Analyses', Behavior Therapy, vol. 57, no. 2, pp. 355-373. https://doi.org/10.1016/j.beth.2025.09.004