Roles of LIM kinases in central nervous system function and dysfunction
Publication date
2015-12-21
Authors
Cuberos, H.
Vallée, B.
Vourc'h, Patrick
Tastet, J.
Andres, Christian R
Bénédetti, H.
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Supervisors
Document Type
Article
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taverne
Abstract
We finally present the existence of a cofilin-independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.
Keywords
LIM kinase 1, LIM kinase 2, Neurodegenerative disease, Neurodevelopmental disease, Neuronal function, Taverne, Biochemistry, Biophysics, Cell Biology, Genetics, Molecular Biology, Structural Biology, General Medicine
Citation
Cuberos, H, Vallée, B, Vourc'h, P, Tastet, J, Andres, C R & Bénédetti, H 2015, 'Roles of LIM kinases in central nervous system function and dysfunction', FEBS letters, vol. 589, no. 24, pp. 3795-3806. https://doi.org/10.1016/j.febslet.2015.10.032